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Anemia-Related Symptoms Fatigue Weakness Muscle weakness Pale/yellowed skin Rapid heartbeat Heart palpitations Shortness of breath Swollen/sore/smooth tongue Headaches Nausea Diarrhea Indigestion Incontinence Appetite problems Weight gain or weight loss Dizziness or faint feeling Nerve-Related Symptoms Nerve problems, such as tingling or numbness Mental health issues, such as depression Memory loss Dizziness Confusion Dementia Imbalance/trouble walking or standing Irritability Vision loss What Causes B12 Deficiency

Pernicious Anemia: This is an autoimmune disorder where the body mistakenly attacks a protein in the stomach called "intrinsic factor." Without this protein, you simply cannot absorb B12 from food, making injections a lifelong necessity

Eur J Pharmacol 1981